See the FAQ at EndNote.
The university has a site license for the EndNote product and makes it available to all Virginia Tech faculty, staff, and students.
This product may be installed on any machines owned by the University. You may install it on personally owned machines if you are a graduate student, undergraduate student, faculty member or staff member of the University.
You have to be connected to the campus network, including the Virginia Tech VPN, to download EndNote from the Software Distribution Office site. Once downloaded and installed, check periodically to see if there have been updates.